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additional:chapter17 2018/11/25 23:17 additional:chapter17 2018/11/25 23:17 current
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  - External validation aims to assess generalizability to 'similar, related populations' ({{additional:justice.generalising.annintmed1999.pdf| Justice 1999}}; {{additional:debray_framework_jce_2015.pdf|Debray 2015}}).   - External validation aims to assess generalizability to 'similar, related populations' ({{additional:justice.generalising.annintmed1999.pdf| Justice 1999}}; {{additional:debray_framework_jce_2015.pdf|Debray 2015}}).
If random splits are made, we assess internal validity; this practice should be abolished. If non-random splits are made, e.g. in time, or by place (centers, countries), we assess generalizability. Here our aim should be to quantify heterogeneity in performance rather than a single estimate of 'performance in new data' ({{additional:austin_external_validation_jce_2016.pdf|Austin 2016}}, {{additional:austin_validation_bmc_2018.pdf|2017}}; {{additional:riley_external_validation_bmj_2016.pdf|Riley 2016}}). If random splits are made, we assess internal validity; this practice should be abolished. If non-random splits are made, e.g. in time, or by place (centers, countries), we assess generalizability. Here our aim should be to quantify heterogeneity in performance rather than a single estimate of 'performance in new data' ({{additional:austin_external_validation_jce_2016.pdf|Austin 2016}}, {{additional:austin_validation_bmc_2018.pdf|2017}}; {{additional:riley_external_validation_bmj_2016.pdf|Riley 2016}}).
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Steyerberg, internal validation {{additional:steyerberg.internalvalidation.jce2001.pdf|JCE 2001}} \\ Steyerberg, internal validation {{additional:steyerberg.internalvalidation.jce2001.pdf|JCE 2001}} \\
Steyerberg&Harrell, perspective on internal and external validation {{additional:steyerberg_harrell_internal_and_external_validation_jce_2015.pdf|JCE 2015}} \\ Steyerberg&Harrell, perspective on internal and external validation {{additional:steyerberg_harrell_internal_and_external_validation_jce_2015.pdf|JCE 2015}} \\
-Steyerberg, role of small and large sample size for independent validation: +Steyerberg, role of small and large sample size for independent validation: **the waste by data splitting** 
-{{additional:steyerberg_validation_waste_jce_2018.pdf| the waste by data splitting}} \\+{{additional:steyerberg_validation_waste_jce_2018.pdf| JCE 2018}} \\
additional/chapter17.txt · Last modified: 2018/11/25 23:17 by ewsteyerberg
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